Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.

Duotrol 2.5 mg/500 mg Tablet SR is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

Duotrol 2.5 mg/500 mg Tablet SR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.

Duotrol 2.5 mg/500 mg Tablet SR is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Duotrol 2.5 mg/500 mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Duotrol 2.5 mg/500 mg Tablet SR may be needed. Please consult your doctor.Duotrol 2.5 mg/500 mg Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.